Gregory Buti, PhD

Massachusetts General Hospital
Boston, MA

I am a researcher in the field of medical physics in radiation oncology. The primary focus of my current research is the improvement of radiation target volumes with the ultimate goal of better managing the trade-off between sparing healthy tissue and the risk of tumor recurrence in radiation therapy. The improvements I have explored in my research career have been primarily on two fronts, first, quantifying treatment confidence levels, and second, using probabilistic modeling to optimize dose delivery to the tumor given dose limits to normal tissues. My work in this area has led to novel ways to use probabilistic treatment planning, a novel framework that incorporates the probability of tumor presence in the optimization process. These studies are presented in several peer-reviewed articles, and the concepts introduced in these studies have been adopted by researchers in the field of probabilistic planning. My research is guided by the need to bridge the gap between the practice of radiation oncology and the formalism of physics. By translating clinical knowledge and experience into mathematical algorithms and physical models, my goal is to develop a model-based implementation of risk assessment that can support and complement current clinical practice.

Disclosures:

  • Employment: none
  • Compensation: none
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  • Leadership: none