Rosa Nadal, MD

I am a medical oncologist specializing in genitourinary (GU) oncology. I began my career as a trialist and translational researcher, focusing on the clinical development of novel immunotherapeutic strategies and the evaluation of biomarkers for GU malignancies, with particular emphasis on bladder and kidney cancers. I have continued to investigate innovative immunotherapies, including T-cell-based approaches for kidney cancer. This work included conducting a clinical trial of HERV-E TCR-transduced T cells for patients with metastatic clear cell renal cell carcinoma. This trial represents the first cellular therapy targeting peptides derived from a human endogenous retrovirus in cancer. My translational research has focused on developing alternative methodologies for quantifying circulating engineered T cells following adoptive transfer, characterizing the molecular features of cell infusion products using multi-omics analysis, and identifying biomarkers to predict treatment response. I recently joined the faculty of Fred Hutchinson Cancer Center as an Associate Professor at the University of Washington School of Medicine.